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    Long-Term Insoluble Anti-Biofilm Protection Nanoparticle

  • Unique ID
    • :
  • TO83010
  • Technology Status
    • :
  • Available
  • Technology Readiness Level
    • :
  • TRL8
  • Published on
    • :
  • 9th Oct 2018
  • Updated on
    • :
  • 17th Oct 2018

  • Technology Overview

    Biofilm is the main form for bacteria and within the biofilm it is highly resistant to disinfectants, antibiotics or the host immune system. Biofilm is therefore extremely hard to get rid of and is associated with most human infections (up to 80%). Biofilm forms and impairs the function of almost any product or equipment stored or operated in wet or humid environments.

    A small size (nano-size or larger), proprietary compound with very high antimicrobial activity (7 log reduction at 1% /wt) has been developed. It is able to impart almost permanent antimicrobial properties to a wide range of materials. The antimicrobial effect is rapid and only upon contact, therefore ideal for preventing formation of biofilm and biofouling on the material surface. The particles are non-leaching so there are no toxicological or environmental effects. The technology can be either embedded or applied as coating, depending on the material and desired use. Originally developed for use in dental materials, the technology is now available for further development for other applications which require biofilm protection.

    Technology Features & Specifications

    • Highly effective: 7 log reductions at 1% /wt
    • Broad spectrum: gram negative, gram positive, fungi
    • Long term (potentially permanent)
    • Compatible with many materials (embedded or coating)
    • Safe, non-soluble, non-leaching
    • Unlikely to induce resistance

    Potential Applications

    • Food Industry: fresh food packages, manufacturing floor, food processing surfaces
    • Agriculture: Greenhouse surfaces, piping, water tanks
    • Shipping: Antifouling
    • Air/Water systems: filters, seals, water storage tanks, piping, membranes
    • Textile: sportswear, technical/nonwoven
    • Consumer: personal and oral hygiene products, baby products, furniture or paint products
    • Dental materials: restoratives, adhesives, sealants, varnish
    • Medical devices: wound dressings, catheters and tubing, implants, hospital surfaces

    Market Trends and Opportunities

    There is major, unmet need for highly active, long-term and non-soluble antimicrobial protection, in many industries. Currently there is no such technology on the market.

    Customer Benefits

    The available antimicrobial technologies are either short-term (soluble), toxic or inducing resistance. Long-term, non-toxic and highly effective protection is not yet available and is needed for many market and applications.

    Keywords : ,

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