Technology Features & Specifications
A Swedish company has developed a novel nanocellulose-based filter paper capable of removing even the smallest and most resistant to disinfection viruses from protein solutions in principle as easily as brewing coffee. The nanocelllulose-based virus removal filter paper combines excellent performance (in terms of virus clearance, flow properties, and protein throughput) with unparalleled cost-efficiency, which can dramatically improve the biosafety of cell therapies with little additional cost. The platform has been validated through numerous external validations with top-global biopharmaceutical industry.
The technology is useful in all steps of bioprocessing, where virus safety is desired or stipulated for regulatory approval, including both upstream and downstream processing. Nanofiltration for ATMPs is an emerging field of application for virus removal filters considering the large number of ATMPs currently tested in clinical trials.
- High virus clearance, incl. ≥4 log10 removal of parvoviruses
- High throughput; including animal-derived and recombinant chemically defined protein-based supplements;
- High robustness and inertness; suitable to process media that contain microelements and Pluronics
- Unparalleled cost-efficiency, compared to competitor's analogues;
- High flexibility to tailor the filter properties and sizing to particular demands of customer's ATMP bioprocess.