Technology Features & Specifications
This biochemical quantifying technique enables a better understanding of the chemical interactions in plasma in real time. The method allows continuous monitoring using the observational heat rate that is proportional to the reaction rate of lipolysis. This proportionality is used for estimation of lipoprotein lipase quantity in the plasma. Primarily, changes in the heat rate are monitored at constant temperature. Entire measurements can be carried out in real-time in non-diluted plasma. The method is easily automated and offers a new way to analyze any dysfunction in the plasma lipoprotein metabolism, which has hitherto not been achieved by any other technique.
- Characterisation of plasma samples for analysis of dysfunctions in lipoprotein metabolism
- Testing of drug candidates and regulators under physiological conditions
- Detection of diseases caused by dysfunctional lipoprotein lipase
- Use in clinical labs for identifying the cause of elevated levels of plasma triglycerides in patients
Market Trends and Opportunities
According to Frost and Sullivan’s estimates, in 2003 alone, 7.2 billion clinically reportable results were produced in laboratories in the United States, of which 5.6 billion tests were used in immunoassay techniques and clinical chemistry to assess various biochemical and immuno-molecules. The size of the biochemical analysis market in laboratories and hospitals is expected to be around $6.1 billion by 2021. The increase in demand for early diagnosis of lifestyle diseases, such as diabetes, obesity, and so on makes the biochemical analysis market attractive.
The biochemical technique is highly sensitive, fully automated and does not require any sample preparation. The entire plasma can be used for analysis without dilution and the results can be monitored in real time. Total time from loading of sample to sample analysis only requires 30 minutes and is a less laborious and time consuming testing method compared with other assays. The initial rates and kinetics of the complete lipolysis process can also be measured. The technique is highly useful for drug companies and pharmaceutical industries for testing of regulators of lipid metabolism and drug candidates more efficiently