Technology Features & Specifications
The invention is a rapid and reliable method for generating LAVs. The total time taken from isolation of a wild-type viral strain to the generation of a suitable LAV candidate is only about 10 weeks, a significant reduction from the time taken to generate LAVs by using conventional methods. A ZIKV LAV generated using this method was shown to be safe and immunogenic, and successful in preventing ZIKV associated mortality in animal models.
This new method can be used for manufacturing safe and effective LAVs for prevention of human infectious diseases such as RSV, ZIKA and Dengue and animal viral diseases.
LAVs to prevent human and animal viral diseases can be generated quicker than convention methods.